Investor profile

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Cowtown Angels

Angel syndicate

USHealthtechBio/PharmaAI/MLFintechB2B SaaSDeep TechOther

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Investment thesis

Cowtown Angels is Fort Worth's premier angel investor network, operating as a program of TechFW (a non-profit supporting the regional tech ecosystem), connecting 150+ accredited investors with innovative early-stage startups. The group deploys capital collectively—$27M+ across 46+ companies since 2012—while providing knowledge, mentoring, and advising opportunities alongside funding. Members collaborate on due diligence and leverage diverse industry expertise spanning biotechnology, life sciences, SaaS, fintech, agritech, medical devices, advanced materials, and consumer products. As Jorge Varela, an early leader, put it: 'We are truly mavericks and have no fear of interesting deals.' The network also co-invests and syndicates deals with other Texas angel groups through the Alliance of Texas Angel Networks (ATAN), aiming to keep high-quality Texas startups in Texas while building a job-creating entrepreneurial infrastructure in Fort Worth.

Notable quotes

It is, in my opinion, an exercise in collective capitalism.

Les Kreis · Fort Worth Inc. – 'Cowtown Angels: More Dolphin Tank Than Shark Tank' · 2021

We are truly mavericks and have no fear of interesting deals. Although most of our investments are in life sciences and high technology, including cloud based solutions to enterprise solutions, we are also in consumer deals including a children's game and health food.

Jorge Varela · ACA Member Profile – Angel Capital Association Blog · 2015-06-08

The Cowtown Angels recognized early that STL's chip cooling technology would be essential to the next generation of data center infrastructure, and the acquisition by Vertiv validates their vision.

Caitlin McMinn · Dallas Innovates – 'Cowtown Angels Portfolio Co. Strategic Thermal Labs Acquired by Vertiv' · 2026-05-12

Team

Bill Buechele

Chairman

HealthtechDeep TechB2B SaaS

Caitlin McMinn

Executive Director, TechFW

Deep TechAI/MLHealthtech

Kaison Giles

Investment Team Member

HealthtechAI/ML

Ryan Brown

Investment Team Member

HealthtechDeep Tech

Les Kreis

Founding Member / Steering Council

FintechHealthtechConsumer

Jorge Varela

Founding Member / Early Leader

B2B SaaSHealthtechConsumer

Recent investments

CompanyRoundSizeDate
KlinriskSeed2025
Glidance Inc.Seed$100k2025
TympanogenSeed2025
Strategic Thermal LabsSeed2024-04
Green Steel EnvironmentalSeed$115k2025
VenoStentSeries A$20m2023-07-19
Zyl TherapeuticsSeries B2022-06-03
Encore VisionSeed$750k2014-01
E-Mist InnovationsSeed
Cognition TherapeuticsSeries B2015-07-22

Frequent co-investors

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