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Empirical Ventures

United KingdomEuropeDeep TechBio/PharmaHealthtechClimateAI/ML

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Investment thesis

Empirical Ventures is a specialist deep tech and life sciences venture capital firm that backs 'Venture Scientists' — PhD-trained technical founders who apply rigorous scientific methodology to company building. Their core thesis is that the greatest transformative companies of the next 30 years will be built by scientists who combine exceptional scientific talent with innate entrepreneurial drive. The firm targets university spinouts and science-led startups in areas that are difficult to diligence for generalist investors, focusing on entirely new technologies developed from fundamental research with IP-rich innovations and competitive defensibility. They invest in solutions to real problems across Life Sciences, Advanced Materials, TechBio, Photonics and Quantum Hardware, Robotics and Automation, AgTech and DeepTech that address climate change, resource scarcity, and healthcare accessibility. Most venture capital chases narratives; Empirical Ventures chases evidence, creating high conviction, diversified portfolios across scientific disciplines through rigorous, evidence-led due diligence.

Notable quotes

The greatest companies of the next 30 years will be built by scientists. We call them 'Venture Scientists' – founders who bring rigorous scientific methodology to company building. But for too long, these founders have been underestimated or misunderstood by generalist investors. This £10m commitment from the British Business Bank allows us to back these Venture Scientists with the conviction they deserve.

Dr. Johnathan Matlock · Pulse2.com / British Business Bank announcement · 2026-03

Most venture capital chases narratives. We chase evidence.

Dr. Johnathan Matlock · LinkedIn post

Recent investments

CompanyRoundSizeDate
SilveraySeed$9m2026-06-22
DiPOLE SystemsSeed$7m2026-06-18
CaudalSeries A$5m2026-05-27
FermtechSeed$1m2026-04-08
OrthofuseSeed$3m2026-02-12
Hot GreenPre-seed$1m2025-10
BoobyBiomeSeed$3m2025
MitoRx Therapeuticsunknown2024
EnsiliTechunknown2024
Argonaute RNAunknown2024

Frequent co-investors

VC firmDeals together
Oxford Science Enterprises1
PXN Ventures1
ACF Investors1
Elbow Beach1
British Business Bank1

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