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Framework Ventures

USGlobalFintechAI/MLDeep TechB2B SaaSOther

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Investment thesis

Framework Ventures is a San Francisco-based, crypto-native venture capital firm founded in 2019 by Vance Spencer and Michael Anderson. The firm was arguably the first VC to 'go all in' on the emerging Decentralized Finance (DeFi) ecosystem, making seminal early investments in multi-billion dollar protocols like Chainlink, Aave, Synthetix, and The Graph. Framework takes a high-conviction, lead-investor approach to early-stage rounds, with check sizes typically ranging from $250k to $40 million. Beyond DeFi, the firm has expanded into additional maturing verticals including AI, blockchain infrastructure, Web3 gaming, and Layer 1 networks. Framework believes the future is being built at the intersection of blockchain, AI, robotics, energy, and fintech, and differentiates itself by actively building alongside founders — combining strategic capital with deep operational and technical expertise.

Notable quotes

The Graph is one of the most beloved protocols in the blockchain world, on par with Chainlink and Ethereum. We couldn't be happier to back Yaniv and the team, and we look forward to helping grow the decentralized network when it launches.

Michael Anderson · The Graph $5M raise announcement, Medium / The Graph Blog · 2020-06-30

Big focus of VC investments is tokenization.

Michael Anderson · CNBC interview · 2024-08-16

We believe the future is being built at the intersection of blockchain, AI, robotics, energy, and fintech.

Framework Ventures · LinkedIn post, Framework Ventures · 2025-06-26

Team

Michael Anderson

Co-founder

FintechAI/MLDeep TechOther

Nick Trileski

Partner

Deep TechAI/MLOther

Parker Edwards

Partner

FintechOther

Rajiv Patel-O'Connor

General Partner

Deep TechOther

Ryan Barney

Partner

FintechOther

Vance Spencer

Co-founder

FintechAI/MLDeep TechOther

Recent investments

CompanyRoundSizeDate
ChainlinkToken/SAFT2019-01-01
AaveToken/SAFT2019-01-01
SynthetixToken Purchase2019-01-01
The GraphSAFT$5m2020-06-30
Jito LabsSeed2022-01-01
HyperliquidSeed2022-01-01
PlasmaSeries A$21m2025-02-13
MeanwhileSeries A$40m2025-04-10
Unto LabsSeed$14m2025-04-29
Uranium DigitalPre-Seed$2m2024-12-12

Frequent co-investors

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