Investor profile
Madrona Venture Group
VC
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Madrona is a full-stack venture partner dedicated to backing founding teams from incubation and seed through acceleration stages, with a strong base in Seattle and the Pacific Northwest and a growing presence in Silicon Valley. The firm looks for founders who care deeply about why a problem exists and have the passion and skill to build lasting, significant companies — particularly in applied AI, intelligent applications, AI-enabled biotech, cloud infrastructure, developer platforms, and next-generation consumer applications. With $770 million in Fund X and Acceleration Fund IV (2025), Madrona targets approximately 30 pre-seed, seed, and Series A companies and 12 Series B/C companies, leveraging its deep relationships with Amazon and Microsoft and over 30 years of experience navigating major technology inflections — from the Internet and SaaS to cloud and applied AI. As the firm states: 'We believe that domain-specific applications of AI in sectors as varied as travel and life sciences, agentic-first consumer and commercial solutions, and horizontal, functional layers that reduce friction between the models, workflows, and end customers are all areas where transformative companies will be built.'
Notable quotes
“The Madrona team has always believed that a healthy mix of prepared and curious minds can anticipate how customer problems, technological disruptions, novel business models, and, of course, exceptional founding teams are brought together to positively change the world. We will continue to leverage a deep Seattle perspective (shaped by our close relationships with and understanding of Amazon and Microsoft) alongside a strong Bay Area presence to provide founders with the best of both worlds.”
“We believe that domain-specific applications of AI in sectors as varied as travel and life sciences, agentic-first consumer and commercial solutions, and horizontal, functional layers that reduce friction between the models, workflows, and end customers are all areas where transformative companies will be built.”
“We have worked closely with Karan for over a decade and been consistently impressed with how he earns the trust of founders and takes a hands-on approach in working with early-stage companies. He is a dynamic, creative problem solver who brings a full-stack approach, including company building expertise, long-term capital allocation, exceptional company engagement, and overall good judgment.”
Team
Scott Jacobson
Managing Director
Karan Mehandru
Managing Director
Tim Porter
Managing Director
Vivek Ramaswami
Partner
Sabrina Albert (Wu)
Partner
Recent investments
| Company | Round | Size | Date |
|---|---|---|---|
| Gray Swan | Series A | — | 2026-05-28 |
| Axiom Math | Series A | $200m | 2026-03-13 |
| Temporal Technologies | Series D | $300m | 2026-02-17 |
| Runway | Series C | — | 2023-06-01 |
| Snowflake | Series B | — | 2018-01-01 |
| Smartsheet | Series A | — | 2012-01-01 |
| Redfin | Series A | — | 2006-01-01 |
| Deepgram | Series B | — | 2022-01-01 |
| Pulumi | Series B | — | 2021-01-01 |
| Rover | Series A | — | 2013-01-01 |
Frequent co-investors
| VC firm | Deals together |
|---|---|
| Alumni Ventures | 15 |
| Andreessen Horowitz | 12 |
| Greylock | 10 |
| Menlo Ventures | 9 |
| Sequoia Capital | 8 |
| Tiger Global Management | 7 |
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