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Polaris Partners

USSGIEGBHealthtechBio/PharmaAI/MLB2B SaaSEnterpriseDeep Tech

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Investment thesis

Polaris Partners is a Boston-based venture capital firm with nearly 30 years of experience backing transformational healthcare and biotech companies. The firm operates three specialized funds: a core venture fund focused on healthcare (digital health, consumer-centric businesses, patient/provider solutions, data science) and life sciences (molecules, platforms, therapeutics, genomics); a Polaris Growth Fund supporting profitable, founder-owned B2B software and technology-services companies with $4–20M revenue; and a Polaris Innovation Fund that accelerates the commercial and therapeutic potential of early-stage academic research. Polaris describes itself as 'not just investors' but 'builders'—board members, entrepreneurs, scientists, and operators who partner deeply with founders from seed through growth, with 150+ years of combined investment experience, 400+ companies funded, 100+ exits, and 60+ therapies brought to market.

Notable quotes

Our firm divides its resources between healthcare and IT deals and writes checks from $50,000 to $60 million.

Terry McGuire · StrictlyVC interview · 2014-01-21

With Fund VI, we will continue our strategy of identifying compelling opportunities, investing early and closely partnering with great entrepreneurs and scientists.

Terry McGuire · Fierce Biotech – Polaris Fund VI announcement

The Polaris team not only creates great companies that change the world, but they go out of their way to treat everyone fairly—founders, employees and other investors. It's been a privilege to work with them.

Dr. Bob Langer · polarispartners.com – homepage testimonial

Recent investments

CompanyRoundSizeDate
Tavo BiotherapeuticsSeries A$17m2026-06-02
EpiBiologicsEarly Stage VC2025-10-31
Zag BioEarly Stage VC2025-10-25
Auron TherapeuticsEarly Stage VC2025-12-23
Alnylam PharmaceuticalsEarly Stage VC
Akamai TechnologiesEarly Stage VC
Editas MedicineEarly Stage VC
Dyno TherapeuticsSeed/Early Stage VC
Dewpoint TherapeuticsEarly Stage VC
Neumora TherapeuticsEarly Stage VC

Frequent co-investors

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