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Analyse your fitInvestment thesis
The Column Group (TCG) is a science-driven venture capital firm that makes significant financial and operational commitments to build early-stage drug discovery companies based on their unique scientific platforms and potential to deliver multiple breakthrough therapeutics. TCG's investment strategy runs counter to the prevailing trend in life sciences venture capital toward assembling diversified portfolios of later-stage, single product-oriented companies. Instead, TCG takes the long view in making investments, recognizing that significant time is often required to generate significant value. The firm assembles a focused portfolio of 'big idea' companies, each built from the ground up with platforms capable of generating multiple differentiated product opportunities. TCG deploys an edge-to-edge investment model, supporting companies from inception through exit through an ecosystem of funds including Platform funds, Opportunity funds, TCG Labs-Soleil, and TCG Crossover (TCGX).
Notable quotes
“We are grateful for the strong support for our model and are pleased by the significant interest generated from our existing investors, with room for a handful of new investors. Since 2007, TCG has been focused on assembling a focused portfolio of 'big idea' companies, each built from the ground up with platforms capable of generating multiple differentiated product opportunities.”
Team
Tim Kutzkey
Managing Partner
Leon Chen
Partner
Sarah Hymowitz
Partner
David V. Goeddel
Partner
Cariad Chester
Partner
Recent investments
| Company | Round | Size | Date |
|---|---|---|---|
| Atavistik Bio | Series B | $120m | 2025-12 |
| Nilo Therapeutics | Series A | $101m | 2025-10 |
| Eikon Therapeutics | Series D | $350m | 2025-02 |
| A2 Biotherapeutics | Series C | $80m | 2025-01 |
| Carmot Therapeutics | Acquisition | $3.3b | 2023-12 |
| Revolution Medicines | IPO | — | — |
| Peloton Therapeutics | Acquisition | $2.4b | 2019-05 |
| Aragon Pharmaceuticals | Acquisition | $1.0b | 2013-08 |
| NGM Biopharmaceuticals | IPO | — | — |
| RAPT Therapeutics | IPO | — | — |
Frequent co-investors
| VC firm | Deals together |
|---|---|
| Nextech Invest | 2 |
| Lux Capital | 2 |
| Samsara BioCapital | 2 |
| ARCH Venture Partners | 1 |
| Atlas Venture | 1 |
| Cure Ventures | 1 |
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