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Third Rock Ventures

VC

USBio/PharmaHealthtechDeep TechAI/ML

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Investment thesis

Third Rock Ventures operates on a distinctive 'Discover-Launch-Build-Transform' methodology, believing that breakthrough science merged with operational rigor creates transformational opportunities in life sciences. Rather than investing in fully-formed companies, the firm collaborates with world-class scientific founders and expert advisors to actively shape company formation from inception — defining structure, vision, strategy, and leadership before launch. Third Rock focuses on identifying emerging fields at the intersection of science and unmet medical need, with a priority on areas such as oncology, rare genetic disorders, cardiovascular disease, neuropsychiatry, autoimmune diseases, and gene/cell therapy. The firm's hands-on approach spans drug discovery, clinical strategy, business operations, and talent acquisition, with partners typically taking board seats and playing active governance roles throughout the company lifecycle.

Notable quotes

We believe in a mentality of Third Rock forever.

Kevin Gillis · Fierce Biotech · 2022-06-15

One of Third Rock's founding principles is the importance of collaboration and a philosophy of group genius. With this as a core value, we employ an evergreen approach to bringing together the best and brightest across the industry.

Robert Tepper · First Word Pharma · 2024-01-25

Our founding vision was based on an operating model rooted in a team-oriented approach, cultivated through group genius.

Kevin Starr · Forbes · 2016-10-31

Team

Robert Tepper

Co-Founder, General Partner

Bio/PharmaDeep TechHealthtech

Abbie Celniker

Partner

Bio/PharmaHealthtech

Kevin Gillis

Partner & COO

Bio/PharmaEnterprise

Jeffrey Tong

Partner

Bio/PharmaDeep Tech

Kevin Munnelly

Partner

Bio/PharmaHealthtech

Mark Levin

Co-Founding Partner

Bio/PharmaDeep Tech

Recent investments

CompanyRoundSizeDate
Syremis TherapeuticsSeries A$165m2025-12-18
Azalea TherapeuticsSeries A$82m2025-11-01
ARTBIOSeries B$132m2025-07-01
Trace NeuroscienceSeries A$101m2024-11-12
Candid TherapeuticsSeries A$370m2024-09-09
Marea TherapeuticsSeries A$190m2024-01-01
Blueprint MedicinesSeries A2011-01-01
Sage TherapeuticsSeries A2011-01-01
Editas MedicineSeries A2013-01-01
Agios PharmaceuticalsSeries A2010-01-01

Frequent co-investors

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