Investor profile
Calculus Capital
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Calculus Capital is a pioneer in the UK tax-efficient investment space, having launched the UK's first approved EIS fund in 1999. The firm specialises in creating and managing EIS and VCT funds that build diversified portfolios of innovative, entrepreneurial UK growth companies — with a particular focus on technology, life sciences, and entertainment/media. Calculus targets smaller, unquoted UK businesses with strong management teams and high growth potential, providing development and scale-up capital typically in the £1m–£7m range per round. The firm takes an active, partnership-oriented approach, frequently taking board seats and supporting portfolio companies through multiple funding rounds to profitable exit.
Notable quotes
“It was a relatively inexpensive sector for investors to get into; there was strong consumer demand for quality content.”
“We were attracted to the company not only for its novel science, but its exceptional management team.”
“It's been a real pleasure working with Chris McCullough and the Rotageek team over the past five years.”
Team
John Glencross
CEO & Co-Founder
Dominic Harris
Head of Portfolio Management
Robert Davis
Investment Director
Recent investments
| Company | Round | Size | Date |
|---|---|---|---|
| Resurrect Bio | Series A | — | 2026-02-17 |
| Trogenix | Series A | $88m | 2025-10 |
| Grateful (Grtfl) | Seed | $2m | 2025-10 |
| Laverock Therapeutics | Seed | $28m | 2025-06 |
| EnsiliTech | Seed | $6m | 2025-08 |
| Tagomics | Series A | $9m | 2024-02-21 |
| Optalitix | Series A | $3m | 2024-09-11 |
| Invizius | Series A | — | 2024-09-23 |
| eConsult Health | Series A | $9m | — |
| Wonderhood Studios | Growth | — | — |
Frequent co-investors
| VC firm | Deals together |
|---|---|
| Mercia Ventures | 4 |
| IQ Capital | 3 |
| Lilly (Eli Lilly) | 2 |
| Octopus Ventures | 2 |
| Illumina Ventures | 2 |
| Scottish Enterprise | 2 |
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